摘要: |
脑疾病包括肝性脑病(或肝昏迷),乙型脑炎,儿童智力发育不全,脑瘫,新生儿缺氧缺血脑病以及脑衰老等。研究结果说明:(1)肝性脑病(或肝昏迷)和乙型脑炎患者体液中谷氨酰胺水平升高,这种升高可以作为以上两种疾病的早期诊断;(2)脑瘫,智力发育不全以及脑衰老(动物)等患者,体液中谷氨酸浓度降低而r-氨基酸(GABA)浓度升高,它们可以作为评价大脑损伤程度的指标,同时也有早期诊断这些疾病的价值;(3)适当补充必需氨基酸能控制以上各种脑疾病的发展。 |
关键词: 脑疾病 游离氨基酸 体液 |
DOI: |
分类号:Q593 |
基金项目: |
|
Study on Brain Diseases and Free Amino Acid |
|
Abstract: |
Brain diseases include hepato-encephalopathy,beta-encephalitis,inelligent hypolasia, cerebral palsy, hypoxic-ischemic ercephalopathy and brain aging. The result indicated that:(1)glutamine (Glm) level increased in body fluid of patients with encephalopathy or encephalitie,which is signigicant for early diagnosis of these diseeses;(2)r-aminobutyric acid (GABA) level imcreased and glutamat (Glu) level decreased is in the body fluid and brain regions of patients with cereral palsy、intelligent hypolasia, and brain aging, which may paly a critical role in brain damage and early diagnosis;(3)supplement essential amino acid can restrain devlopment of these brain diseases. |
Key words: brain disease, free amino acid, body fluid. |