| 摘要: |
| 目的：探讨萌动激活赤灵芝孢子粉对小鼠脾细胞IL-2分泌和脾淋巴细胞转化增殖的影响。方法：实验小鼠随机分成实验组(低剂量组4g/kg/d：高剂量组：8g/kg/d)和对照组(与实验组用同体积的生理盐水)，连续用药10天。用3H—TdR掺入法进行检测。结果：与对照组相比萌动激活赤灵芝孢子粉对小鼠脾细胞IL-2分泌有明显促进作用并能明显提高小鼠脾淋巴细胞转化增殖，并有一定的量效关系。结论：萌动激活赤灵芝孢子粉对小鼠免疫功能有明显的促进作用，这可能与其促进细胞因子的分泌和淋巴细胞转化增殖有关。 |
| 关键词: 萌动激活/赤灵芝孢子粉 3H—TdR法 IL-2 淋巴细胞转化增殖 |
| DOI： |
| 分类号:R967 |
| 基金项目: |
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| Effects of Actively Germinating Ganoderma spore on the secretion of IL-2 and the Transformation and Proliferation of mouse splenocyte |
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| Abstract: |
| To explore the action of actively germinating ganoderma spore onthe secretion of IL-2 and the transformation and proliferation of mouse splenocyte.Methods:3H-TdR incorporation scintillation count assays. Results: Compared with the control,the actively germinating ganoderma spore not only dramatically increased the secretion of IL-2 but also enhanced the transformation and proliferation of mouse splenocyte with dose manner. The actively germinating ganoderma spore possesses obviously immuno-promoting effect on mouse immune system and this effect might be related with the secretion of cytokines and the proliferation and transformation of lymphocyte |
| Key words: Actively germinating Ganoderma spore, 3H-TdR incorporation assays IL-2 Transformation and proliferation of lymphocyte |
