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口服抗乙肝转移因子免疫活性研究
邓兆群,闵磊,曹晓春,白瑞珍,屈雪菊
武汉大学基础医学院 武汉 430071
摘要:
采用肌肉和皮内混合免疫方法,将乙肝疫苗给猪接种。全程免疫5次,2个月后,取脾脏和淋巴结制成口服抗乙肝转移因子。在小鼠体内进行了白细胞粘附抑制试验,结果表明口服抗乙肝转移因子具有依赖抗原的特异性免疫活性。
关键词:  生化药物  口服抗乙肝转移因子  免疫活性
DOI:
分类号:S432.2
基金项目:
Immune Activity of Oral Anti-HBTF
Abstract:
Pigs were immunized with hepatitis B vaccine intramuscularly andintracutaneously for five times after every ten days. Two months later, the pig spleen and Lymphnode were drawn to make oral administrating Anti-Hepatitis B Transfer Factor (Anti-HBTF).The result of the Leukocyte Adhesion Inhibition Assay in the mouse indicated that the Anti-HBTF possessed the antigen-dependent immune activity.
Key words:  Biochemical Medicine, Oral administration Anti-Hepatitis B Transfer Factor, Immune Activity