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国产色谱柱在复方氨基酸输液含量测定中的应用研究
陆柳容1,谭仕轩2
1. 广州汉方现代中药研究开发有限公司,广州,510240;2. 广增集团增城市广增药物研究所,增城,511309
摘要:
运用两种国产色谱柱检测复方氨基酸注射液中各氨基酸的含量,分别建立了分离检测方法,优化了梯度洗脱的条件.在waters和agilent的高效液相仪上,两个厂家的色谱柱均显示出较好的分离效果.结果表明国产色谱柱能经济有效的达到质量控制的目的,可以推广使用.
关键词:  国产色谱柱  高效液相色谱法  复方氨基酸输液
DOI:
分类号:Q517
基金项目:
Determination of Amino Acids in Compound Amino Acid Injections by Using Home -Made Column
Abstract:
The determination of amino acids in compound amino acid injections by using two home-made chromatographic columns was studied.Separation and determination methods were established separately.And the gradient elution condition was optimized.Two kinds of column had good result on waters and agilent instruments.This indicated that home-made columns could economically and efficiently reach the goal of quality control,and could be widely used.
Key words:  home made chromatogram column  HPLC  compound amino acid injection