| 摘要: |
| 人纤溶酶原K1-3功能区是一个血管生成抑制因子。以人纤溶酶原k1-3基因在大肠杆菌中表达的重组K1-3蛋白进行鸡胚绒毛尿囊膜(chorioallantoicmembrane,CAM)血管生成抑制活性分析和小鼠B16黑色素瘤抑瘤实验,结果证实重组K1-3蛋白具有抑制毛细血管生成和抗肿瘤活性。 |
| 关键词: 重组K1-3蛋白 抑制血管生成 抑制肿瘤生长 |
| DOI： |
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| Antitumor Activity of Recombinant K1-3 Domain of Human Plasmihogen |
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| Abstract: |
| The recombinant human plasminogen K1-3 domain was assayed for the chorioallantoic membrane(CAM) and mouse B16 melanoma. The results showed that the recombinant product inhibited the growth of CAM angionesis and mouse B16 melanoma. |
| Key words: recombinant human plasminogen K1-3 domain inhibition of the growth of angionesis inhibition of the growth of tumor |
