| 摘要: |
| 海洋放线菌生活的环境如养分、光照、氧气浓度、压力、盐度和温度等与陆地环境存在极大差异，因此海洋放线菌形成了独特的生物化学代谢和生理能力。近年来，海洋放线菌成为生物资源开发和研究的热点。海洋放线菌分布广泛，种类多样。海洋放线菌活性代谢产物具有极强的医药应用潜力，其代谢产物的功能研究及重要代谢产物的开发成为海洋放线菌研究的重要方向。此外，海洋放线菌在环境保护以及生产应用等方面展现出的潜能，引起研究人员极大的兴趣。本文结合近年来海洋放线菌的分离种类与生境、海洋放线菌的研究策略与手段以及代谢产物功能多样性进行了归纳总结，以期对海洋放线菌的认识更全面、系统。 |
| 关键词: 海洋放线菌 种质资源 次级代谢产物 生物活性物质 合成生物学技术 |
| DOI：10.14188/j.ajsh.2021.03.005 |
| 分类号:Q939.9 |
| 基金项目:山西师范大学优质课程（2019YZKC-10）；山西师范大学大学生创新项目（2019DCXM-84） |
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| Advances in the resources， research methods and biological activities of marine actinomycetes |
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LÜ Peishuai1,2, ZHANG Lihong1, XU Fuzhou2, MA Gangqing1
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1.School of Life Science， Shanxi Normal University， Linfen 041000， Shanxi， China;2.Institute of Animal Husbandry and Veterinary Medicine， Beijing Academy of Agriculture and Forestry Sciences， Beijing 100097， China
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| Abstract: |
| The available nutrients， light， oxygen concentration， pressure， salinity and temperature of habitats where marine actinomycetes live are greatly different from those of terrestrial environment， which makes marine actinomycetes develop unique biochemical metabolisms and physiological capabilities. In recent years， marine actinomycetes have become a hotspot in the development and research of biological resources. Marine actinomycetes are widely distributed and diverse. Bioactive metabolites of marine actinomycetes have great potential for medical application. The study on the function of metabolites and the development of important metabolites have become an important direction of marine actinomycete research. In addition， researchers are interested in the potential of marine actinomycetes in environmental protection and production applications. In this paper， the isolation species and habitats， the research strategies and means of marine actinomycetes， and the functional diversity of the metabolites are summarized in order to have a more comprehensive and systematic understanding of marine actinomycetes. |
| Key words: marine actinomycete germplasm resource secondary metabolite bioactive substance synthetic biology technology |
