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| 水产虾蟹microRNA组学研究进展 |
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郭梁1,2,蒋启程1,崇加俊1,陈浩1,欧江涛1,王资生1,钟金城1,2
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1.盐城工学院 海洋与生物工程学院，江苏 盐城224051;2.西南民族大学青藏高原研究院
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| 摘要: |
| MicroRNA是一类广泛存在于真核生物，长度约为18~25个核苷酸的非编码RNA，对靶基因转录后的调控具有重要作用，广泛参与生长发育、免疫、增殖和凋亡等各种生物学过程。本文简要总结了microRNA的生成、调控机制及其检测方法，讨论了虾蟹microRNA对免疫调控、生殖发育、环境胁迫三方面的调节作用，以期促进对虾蟹microRNA研究现状的了解以及为microRNA在虾蟹免疫、生殖发育和应对环境胁迫的调控机制研究提供参考。 |
| 关键词: microRNA组学 虾蟹 免疫调控 生殖发育 环境胁迫 |
| DOI：10.14188/j.ajsh.2020.01.010 |
| 分类号:Q752 |
| 基金项目:国家自然科学基金面上项目(编号:31570176;31872601);国家自然科学基金青年科学基金项目(编号:31000072) |
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| Research progress on microRNA omics in shrimp and crab |
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GUO Liang1,2,JIANG Qicheng1,CHONG Jiajun1,CHEN Hao1,OU Jiangtao1,WANG Zisheng1,ZHONG Jincheng1,2
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1.College of Ocean and Bioengineering, Yancheng Institute of Technology , Yancheng 224005， Jiangsu, China;2.Institute of Qinghai-Tibetan Plateau, Southwest University for Nationalities, Chengdu 610041, Sichuan, China
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| Abstract: |
| MicroRNA（miRNA） is small non-coding RNA of 18~25 nucleotides, which widely exists in eukaryotes. It plays an important role in the post-transcriptional regulation of target genes and is widely involved in biological processes such as growth and development, immunity, proliferation and apoptosis. In this review, the generation, regulation mechanism and detection methods of microRNA are summarized briefly, and the regulation of microRNA in immunity, reproductive development and stress regulation are also discussed. This paper summarizes those results and benefits the understanding of the present situation of the microRNA research in shrimp and crab, and may be helpful for the promotion of the study in non-coding RNA. |
| Key words: miRNAomics shrimp and crab immune regulation reproductive development environmental stress |
