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海南习用药材无柄灵芝质量标准研究
郑雷舒1,黄梦利2,巩圣坚2,刘洋洋2
1.海南康农堂中药有限公司 海南 海口 571127;2.中国医学科学院&北京协和医学院 药用植物研究所海南分所
摘要:
为建立海南习用药材无柄灵芝的质量标准,依据《中国药典》2015年版中药质量标准研制的要求,对无柄灵芝药材的性状、鉴别、检查、浸出物、灰分、含量测定等项目进行研究。本研究明确了无柄灵芝药材的性状和显微结构特征,建立了专属的薄层鉴别方法;规定无柄灵芝多糖含量不得低于0.40%、三萜与甾醇含量不得低于0.40%、水分不得超过18.0%、总灰分不得超过4.0%、浸出物不得低于2.0%,为无柄灵芝药材质量控制及资源开发利用提供科学依据。
关键词:  无柄灵芝  质量标准  多糖  三萜与甾醇
DOI:10.14188/j.ajsh.2019.04.008
分类号:Q949.781.1
基金项目:海南省自然科学基金创新研究团队项目 2017CXTD022 海南省自然科学基金创新研究团队项目(2017CXTD022)
Study on quality standard of Ganoderma Sessilia for Hainan traditional medicine
ZHENG Leishu1,HUANG Mengli2,GONG Shengjian2,LIU Yangyang2
1.Hainan Kangnongtang Traditional Chinese Medicine Co.Ltd, Haikou 571127, Hainan, China;2.Hainan Branch, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Haikou 570311, Hainan, China
Abstract:
To establish the quality standard of Ganoderma Sessilia, a traditional medicinal material in Hainan, the properties, identification, inspection, extract, ash and content determination of Ganoderma Sessilia were studied according to the requirement of the quality standard of Traditional Chinese Medicine of the Chinese Pharmacopoeia 2015 edition. The properties and microstructural characteristics of Ganoderma Sessilia were identified, and the exclusive thin layer chromatography identification method of Ganoderma Sessilia was established. It is stipulated that the content of polysaccharide, triterpenoid and sterol in Ganoderma Sessilia should not be less than 0.40%, water content should not be less than 18.0%, total ash content should not be more than 4.0%, and extracts should not be less than 2.0%, which could provide scientific basis for the quality control, resource development and utilization of Ganoderma Sessilia.
Key words:  Ganoderma Sessilia  quality control  polysaccharide  triterpenoid and sterol