| 摘要: |
| 探讨L-精氨酸(L-Arg)的肾功能保护作用机制及与肌苷的疗效比较。模拟手术肾损伤模型,分别采用放射免疫法和硝酸还原酶法检测手术前后大鼠不同时期尿液β2-MG、血浆NO含量变化。结果表明L-Arg和肌苷均对肾功能损伤有明显保护作用,L-Arg比肌苷更快地促进肾功能的恢复。 |
| 关键词: L-精氨酸 肌苷 一氧化氮 β2-微球蛋白 肾功能 |
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| Effects of L-Arginine and Inosine on Renal Function |
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| Abstract: |
| To investigate the potential role of L-arginine and inosine in renal function protection, operating renal injuried mode was used and the lever of β2-MG in urine and nitric oxide in plasma were determined by radioimmunoassay and nitrate reductase methods on first day before surgery and first,third,seventh day after surgery.Both L-Arg and inosine provided protective effects on renal function significantly, and L-Arg improved renal function more quickly than inosine. |
| Key words: L-arginine inosine nitric oxide(NO) β2-microglobulin(β2-MG) renal function |
