摘要: |
β-sheet类核酸结合域广泛存在于各种DNA特别是RNA结合蛋白中,参与生物体的各种基因调控,是一种重要的反式作用结构域,根据其基本的结构特征,可以推测其与多核苷酸链识别结合的作用机理. |
关键词: 扭结 碱基堆积修复 进化最优原则 长程作用残基 |
DOI: |
分类号:Q52 |
基金项目: |
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Principle of β-sheet Nucleic Acid Binding Domain |
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Abstract: |
β-sheet nucleic acid binding domain is very common in different kinds of DNA and RNA binding proteins.It participates in many gene expressions of the organisms. So, it's a important trans domain. The principle of the recognizing between the domain and the nucleotide strand can be concluded from its basic structural characteristics. |
Key words: kink base stacking repair evolution optimization long term effecting residues |