| 摘要: |
| 用氨甲蝶呤诱发小肠炎后,SD大鼠分别饲喂Gln含量不等的氨基酸营养液,结果表明,72h内,第一组(零剂量组)大鼠的死亡率为66.7%,第二组(含Gln质量分数2%)为16.7%,第三组(活性肽组,含Gln质量分数20%)和第四组(结晶氨基酸液,含G ln质量分数20%)为0,并且第三组和第四组的体重、蔗糖酶活、氨肽酶活、DNA和RNA的含量增加,说明Gln活性肽营养液对小肠具有明显的营养作用. |
| 关键词: 谷氨酰胺 谷氨酰胺活性肽 小肠 氨甲蝶呤 |
| DOI： |
| 分类号:R151 |
| 基金项目: |
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| Nutritional Effect of Glutamine Bioactive Peptide on the Small Intestine of Rats |
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| Abstract: |
| Administration of methotrexate to rats caused severe enterocolitis with 66.7% and 16.7% mortalities within 72 hours in the first group (control group) and the second group (2% Gln) respectively. But the sucrase and aminopeptidase activities,DNA and RNA contents of small intestine in rats of group 3 (glutamine bioactive peptide group) and group 4(20% Gln) were significantly higher than those of group 1 and group 2. These results showed that glutamine bioactive peptide enhanced digestion processes, so it can be used to improve nutritive conditions of the small intestine. |
| Key words: glutamine glutamine bioactive peptide small intestine methotrexate |
