摘要: |
由于叔丁基的特殊结构和性质,叔亮氨酸是重要的医药中间体和不对称合成的手性诱导模板.本文综述了近年来光学活性的叔亮氨酸的合成研究及最新进展. |
关键词: 叔亮氨酸 化学合成法 生物酶法 |
DOI: |
分类号:O621.3 |
基金项目: |
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Progress in the Synthesis of Optically Active tert-Leucine |
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Abstract: |
Owing to the special structure and properties, tert-leucine is an important intermediate in pharmaceutical production and a chiral auxiliary for asymmetric synthesis. Recent progresses of the synthesis of optically active tert-leucine are reviewed in this paper. |
Key words: tert-leucine chemical synthesis enzymatic synthesis |