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酶蛋白分子可及性与等电点关系的研究
吴斌,艾建宇,冯胜彦,陈蔚梅,吴显辉,熊晓然,郭明雄
武汉大学生命科学学院,湖北武汉,430072
摘要:
依据酶的晶体结构数据对它的分子可及性进行了计算和分析,探讨了氨基酸可及性与酶性质的关系,研究了氨基酸可及性和酶等电点之间的关系,发现了氨基酸可及性与酶等电点之间的线性关系.
关键词:  可及性  等电点  氨基酸
DOI:
分类号:Q617
基金项目:
Study on the Relation between Accessibility of Enzyme and Isoelectronic Point
Abstract:
The molecular accessibility of enzyme was calculated and analyzed on the basis of its crystal structure data. The relation between accessibility of amino acids and the property of enzyme was discussed, and the relation between accessibility of amino acids and the isoelectronic point of enzyme was studied. The result showed a linear relation between accessibility of amino acids and the isoelectronic point of enzyme.
Key words:  accessibility  amino acid  isoelectronic point