| 摘要: |
| 对22例胃癌组织及其癌边组织、胃正常组织氨基酸进行了测定.发现胃癌组织氨基酸总量低于癌边组织氨基酸总量,癌边组织氨基酸总量又低于胃正常组织氨基酸总量.癌中组织与癌边组织相比有8种氨基酸明显降低,P＜0.01;其中三种为人体必需氨基酸,三种为生糖氨基酸.胃癌组织与胃正常组织相比3种生糖氨基酸明显降低,P＜005.结果表明:胃癌组织存在明显的氨基酸代谢异常. |
| 关键词: 胃癌组织 氨基酸 |
| DOI： |
| 分类号:R735 |
| 基金项目: |
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| Determination of Amino Acid Content in the Tissue of Human Gastric Cancer and Normal Stomach |
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| Abstract: |
| The distribution of amino acid in the gastric cancer, flanking of the cancer and the adjacent normal tissue from 22 patients with gastric cancer were determined. It was found that the content of amino acid in gastric cancer was lower than that of the flanking area of the cancer. The amino acid content in the latter was lower than that of adjacent normal tissue. The content of eight kinds of amino acid including three essential and three glycogenetic amino acid in gastric cancer was significantly lower than that of the flanking area, P<0.01. The content of the three glycogenetic amino acid in gastric cancer was also lower than that in the adjacent normal tissue, P<0.01. The content of the three glycogenetic amino acid in the flanking area of the cancer was also lower than that in the adjacent normal tissue, P<0.05. The results suggested that a significant disturbance in the metabolism of amino acid would exist in the gastric cancer tissue. |
| Key words: gastric cancer tissue, amino acid |
