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藏药牛尾蒿本草考证及化学成分、生物学作用研究进展
罗雨薇1, 孙桂鸿2, 郭明雄1
1.西藏大学生态环境学院;2.武汉大学泰康医学院(基础医学院)
摘要:
牛尾蒿作为传统中医和藏医、蒙医等传统医药体系中的一种常用药材,其生物学功能十分广泛,在多种藏药复方制剂中发挥作用。现代研究发现牛尾蒿含有多种化学成分,具有不同的生物学活性,应用前景良好。本文通过查阅《月王药诊》《中国医学百科全书·藏医学》等经典文献和权威著作,对藏药牛尾蒿的命名溯源、性味功效及其在复方制剂中的应用情况进行本草考证,并结合文献报导综述了牛尾蒿的主要化学成分及其生物学作用。结果显示牛尾蒿主要含有萜类、挥发油类和苯丙素类等化学成分,具有镇咳平喘、抗虫抗菌、抗氧化抗炎以及抗肿瘤等广泛的生物学作用,在人类和动物疾病治疗方面具有较高的药用价值。
关键词:  藏药  牛尾蒿  化学成分  生物学作用
DOI:
分类号:R931.71
基金项目:西藏自治区中央引导地方科技发展资金项目(XZ202301YD0040C);国家自然科学基金地区科学(32260173)
Research progress in the textual research, the chemical composition and biological effects of Tibetan medicine Artemisia dubia
Sun Guihong
Hubei Provincial Key Laboratory of Allergy and Immunology,Taikang Medical School School of Basic Medical Sciences,Wuhan University
Abstract:
Artemisia dubia, a medicinal material commonly used in traditional Chinese medicine, as well as in Tibetan and Mongolian medical systems, exhibits a broad range of biological functions and is incorporated into various Tibetan medicinal compound preparations. Modern research has revealed that Artemisia dubia contains multiple chemical constituents with diverse biological activities, indicating promising potential for further development and application. In this review, a herbalogical investigation of the Tibetan medicine Artemisia dubia - covering its nomenclature, medicinal properties, and uses in compound formulations - was conducted by reviewing classical texts and authoritative works such as The Moon King’s Medical Prescriptions and the Encyclopedia of Chinese Medicine: Tibetan Medicine. In addition, the main chemical components and biological effects of Artemisia dubia were summarized based on literature reports. The findings indicate that Artemisia dubia primarily contains terpenoids, volatile oils, and phenylpropanoids, which are associated with a wide spectrum of pharmacological activities, including antitussive, antiasthmatic, antiparasitic, antibacterial, antioxidant, anti-inflammatory, and antitumor effects. These properties highlight its significant medicinal value in the treatment of diseases in both humans and animals.
Key words:  Tibetan medicine  Artemisia dubia  Chemical composition  Biological effects